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BMG LABTECH News

Welcome to BMG LABTECH News giving you up to date information on new microplate readers, new applications, software releases and events.

If you would like to submit a news item for inclusion please contact us at marketing.

 

 

tag October 07, 2008
Omega Microplate Readers with Advanced Technology Package
BMG LABTECH's Omega Series of Microplate Readers: Now TR-FRET & AlphaScreen® compatible

The Omega series, including the FLUOstar Omega and POLARstar Omega, is the world's only microplate reader line with Tandem Technology utilizing high-speed UV/Vis spectrometer based absorbance and ultra-sensitive filter based detection in all measurement modes. These multidetection microplate readers are capable of reading absorbance, luminescence, fluorescence intensity, fluorescence polarization and time-resolved fluorescence. Combined with a high intensity xenon flash lamp, assay optimized filters and adjustable gain, the Omega series outperforms any microplate reader in the mid-range market.

The FLUOstar Omega and POLARstar Omega now include an Advanced Assay Technology Package for even more demanding applications including AlphaScreen® and TR-FRET assays such as HTRF® and LanthaScreenTM. With HTRF® certification, LanthaScreenTM Certified Plus status and DLReadyTM certification, BMG LABTECH's innovative Omega Series is the perfect solution for all your microplate based applications.

Established in 1989, BMG LABTECH is a global supplier of microplate measurement and handling systems for basic research and High-Throughput Screening. BMG LABTECH focuses on microplate readers with a wide variety of optical detection systems in conjunction with integrated liquid handling equipment. BMG LABTECH is committed to bringing you innovative technology with the reliability and quality that you expect from a dedicated microplate reader specialist.


more info: http://www.bmglabtech.com

tag October 07, 2008
PHERAstar Plus HTS Microplate Reader Video

pheraplus-video BMG LABTECH UK was recently featured at SBS/Elrig Drug Discovery 2008 (23rd/23th October 2008) in Bournemouth, UK. This video highlights the flagship HTS microplate reader, PHERAstar Plus, and its significant enhancements in sensitivity levels for luminescence and HTRF® assays as well as other notable features. For a full video presentation please click here.



tag August 29, 2008
MARS available for all BMG LABTECH microplate readers
Offenburg - Germany BMG LABTECH GmbH, the worldwide leader in innovative microplate reading technology announces full compatibility of the sophisticated data analysis software MARS for all BMG LABTECH microplate readers.

MARS can now also work on the NOVOstar, NEPHELOstar, the OPTIMA- and OMEGA- series of microplate readers as well as the high-end PHERAstar Plus multi-detection HTS reader. MARS provides quick and easy results and user-defined data processing is done simply by one click of the mouse.

Upgrade to MARS and benefit from the calculation of important parameters such as S/N, Delta F % and Z´. Easy calculation of a standard curve and the Template Manager for building complex data processing protocols are main features of the software. MARS includes powerful sort and order functionality, averaging of raw and blank corrected data, automated or user-defined range adjustment, zoom functions, and a curve fitting library to allow fast calculation of EC50, IC50, r2, and CV values. MARS is also FDA 21 CFR Part 11 compliant.


more info: http://www.bmglabtech.com

tag April 03, 2008
BMG LABTECH announces Collaboration with Invitrogen
Invitrogen's drug discovery products will be tested on certain BMG LABTECH microplate readers, and select BMG LABTECH instruments, such as the PHERAstar and OMEGA series, will be certified for use with specific Invitrogen technology platforms. Initial certifications will focus on Invitrogen's assay systems for key target classes, such as LanthaScreenTM TR-FRET for protein kinases, PolarScreenTM FP technology for nuclear receptors, GeneBLAzer® reporter-gene technology for G protein-coupled receptors and AdaptaTM, a new TR-FRET assay system for lipid kinases. This collaboration will allow BMG LABTECH and Invitrogen to develop and promote joint applications for the drug discovery market.

more info: http://www.bmglabtech.com

tag March 15, 2008
PHERAstar Plus - Flagship for HTS
BMG LABTECH´s PHERAstar Plus sets new standards in HTRF®, luminescence and fluorescence polarization reading

To satisfy the ever-increasing demands of the HTS community a new version of the highly successful microplate reader PHERAstar is available from BMG LABTECH, the PHERAstar Plus. The PHERAstar Plus features Advanced HTRF® / TR-FRET, Advanced Luminescence, and Advanced Fluorescence Polarization reading modes by integrating the latest technological advancements in optics and electronics. Coupled with the new powerful data analysis software package MARS, these new features extend the application versatility of the PHERAstar Plus.

The PHERAstar Plus is a simultaneous dual emission HTS microplate reader offering all leading detection technologies including fluorescence intensity / FRET, fluorescence polarization, time-resolved fluorescence / TR-FRET, laser-based AlphaScreen®, luminescence / BRET, and UV/Vis absorbance. The new instrument provides both enhanced HTRF® performance with market leading Z' and TR-FRET ratio performance and a fourfold increase in luminescence sensitivity. This is made possible by BMG LABTECH's innovations in the modular optical system combined with the unique well-proven detection technology. The PHERAstar Plus is the only microplate reader on the market with five photomultiplier tubes (PMTs) and Simultaneous Dual Emission (SDE) technology optimized for specific reading modes and the capability to capture TR-FRET decay curves in real-time for assay optimization.

The PHERAstar Plus will be delivered with a new version of BMG LABTECH's established Reader Control and a completely new MARS Data Analysis Software with significant ease-of-use enhancements such as S/N, Z', and many other standard calculations. The Wizard creates an easy step-by-step calculation of a standard curve and the Template Manager is an excellent tool for building complex data processing protocols. Thus, user-defined data analysis is done simply with one click of the mouse. Improved robotic integration capabilities, digital signature and the 21 CFR part 11 compliance of MARS complete this new software.

Established in 1989, BMG LABTECH is a global manufacturer of microplate measurement and handling systems for basic research and High-Throughput Screening. We focus on microplate readers with a wide variety of optical detection systems in conjunction with integrated liquid handling equipment. We are committed to bringing you innovative technology with the reliability and quality that you expect from BMG LABTECH. Visit our website for more information on the PHERAstar Plus: www.bmglabtech.com



more info: http://www.bmglabtech.com

tag February 14, 2008
BMG LABTECH releases the new evaluation software, MARS

Offenburg - Germany  BMG LABTECH GmbH, the worldwide leader in innovative microplate reading technology announces the release of the new Microplate Reader Analysis and Data Reduction Software, MARS.

BMG LABTECH´s microplate readers are used in pharmaceutical, biotech, and academic labs. They have been recognized in premier peer-reviewed publications to provide high quality data in the life sciences. Based on a friendly graphical user interface, the MARS software now allows analysis and display of multiple measurement methods and has no limitation regarding the number of data points.

The most common detection modes include absorbance, luminescence, fluorescence intensity, fluorescence polarization, time-resolved fluorescence, and time-resolved fluorescence resonance energy transfer (TR-FRET), to study compound solubility, antioxidant capacity, protein-protein binding, nucleic acid concentration, and second messengers such as ATP and cAMP.

MARS works on the NEPHELOstar, the OPTIMA- and OMEGA- series of microplate readers as well as the high-end PHERAstar multidetection microplate reader. Compatibility for the NOVOstar will be available in April, 2008.

The MARS wizard creates an easy step-by-step calculation of a standard curve and the Template Manager is an excellent tool for building complex data processing protocols. New features include powerful sort and order functionality, averaging of raw and blank corrected data, lock on data trace, automated or user-defined range adjustment, zoom functions, and a curve fitting library to allow fast calculation of EC50, IC50, r2, and CV values.
MARS provides results quick and easy and user-defined data processing is done simply by one click of the mouse.

Digital Signature and the 21 CFR part 11 compliance of MARS complete this new software package.


more info: http://www.bmglabtech.com

tag December 01, 2007
Omega Series - DLReady™

BMG LABTECH´s Newest Series of Multifunctional Readers with Unique High Speed Full Spectrum Absorbance

DLReadyTM certification, awarded by Promega Corp., validates an instrument that has passed the strict performance levels and standards required for the Dual-Luciferase Reporter (DLRTM) assay system. DLRTM is one of the most commonly used luminescence assays for measuring gene transcription in a microplate format. Using firefly and Renilla luciferases as reporter genes, the DLRTM Assay System rapidly quantifies gene expression in transfected cells or in cell-free transcription/translation reactions.

BMG LABTECH´s FLUOstar Omega, POLARstar Omega, and LUMIstar Omega have all been certified by Promega. The Omega is the world´s only DLReadyTM multidetection microplate reader that can capture a full absorbance spectrum (220 to 850 nm) at a resolution of 1 nm. Read times faster than 1 second per well are possible. This makes the Omega the 3rd series of BMG LABTECH life science readers that have been DLReadyTM certified, along with the OPTIMA and Galaxy series and the NOVOstar microplate reader with micropipettor.

For technical information on performing the DLRTM assay on the FLUOstar Omega, POLARstar Omega, or LUMIstar Omega microplate reader, an application note can be downloaded here


more info: http://www.bmglabtech.com

tag July 01, 2007
The New Omega Series

The New Omega Microplate Reader: Another Level of Flexibility

BMG LABTECH has started serial production of the new Omega family of multifunction microplate readers with high resolution, full UV/Vis spectrometer based absorbance. This new family of readers combines all of the speed, sensitivity and flexibility needed for life science applications and research.

The Omega line is made up of four models: the SPECTROstar Omega, a spectrophotometer; the LUMIstar Omega, a luminometer; the FLUOstar Omega, a multidetection reader (fluorescence, time-resolved fluorescence, luminescence, and absorbance); and the POLARstar Omega, a multidetection reader with additional simultaneous dual emission and fluorescence polarization mode. Due to the absolute modular concept of the Omega family of readers, the SPECTROstar Omega and the LUMIstar Omega are entirely upgradeable to a multidetection microplate reader whenever the need for fluorescence based experiments arrives.

The Omega readers are fast, reading a 384-well plate in less than 15 seconds. In addition, the Omega series offers a number of outstanding features: integrated injectors with direct access to the measurement position; photometric spectral scans; top and bottom reading; well scanning; temperature control up to 60°C; shaking; stacker and robot compatibility; and a gas vent connection to support all major types of cell based assays.

Main technical innovations of the new reader series include extensive upgradeability, as well as the capability of capturing a full absorbance spectrum (220 to 850 nm) in one second per well, at a fantastic resolution of 1 nm. Furthermore, a new UV-enhanced flashlamp and high speed plate shaking are now available.

The Omega series of microplate readers will be delivered with a new powerful software package, including new proprietary evaluation software. This evaluation software displays and analyzes endpoint, kinetic and spectral data through comprehensive data reduction algorithms and various curve fitting options. It is compatible with the new Windows Vista" operating system and is fully compliant with FDA regulation 21 CFR Part 11.


more info: http://www.bmglabtech.com

tag January 03, 2007
Enhanced AlphaScreen® and FP in the PHERAstar
BMG LABTECH announces further enhancements to its multimode microplate reader PHERAstar.

These enhancements result in better performance of both AlphaScreen® and FP assays.

In addition to simultaneous dual emission reading in all leading detection modes (F, L, TR-FRET, BRET, FRET and FP) the PHERAstar now also has improved AlphaScreen® performance with four times faster plate read speed and market leading Z' factors for AlphaScreen® assays.

FP specification has also been enhanced and improved. With 1.0 mP SD (at 1 nM fluorescein in 384-well plates) the PHERAstar widens the gap even further from the competition.
Finally the speed of reading has been increased by up to 50%.

No matter what type of assay you run, the PHERAstar offers you the speed and flexibility that you would expect from a world leading multimode microplate reader.


more info: http://www.bmglabtech.com

AlphaScreen is a registered trademark of PerkinElmer, Inc.

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